文章基本信息

标题：Safety assessment of Spirulina platensis through sprague dawley rats modeling
其他标题：Safety assessment of Spirulina platensis through sprague dawley rats modeling
本地全文：下载
作者：BASHIR, Shahid ; SHARIF, Mian Kamran ; JAVED, Muhammad Sameem 等
期刊名称：Food Science and Technology (Campinas)
印刷版ISSN：0101-2061
电子版ISSN：1678-457X
出版年度：2020
卷号：40
期号：2
页码：376-381
DOI：10.1590/fst.41918
出版社：Sociedade Brasileira de Ciência e Tecnologia de Alimentos
摘要：Health safety of spirulina (Spirulina platensis) for food application was evaluated through hematology and histopathology of liver, spleen and kidney in Sprague Dawley rats fed on three isoproteic diets maintained to 10% protein for forty five days. Three groups of rats were maintained as control diet casein (R-C); diet containing crude spirulina (R-S) and diet containing purified spirulina protein (R-SPI). Hematological profile of the rats group fed on spirulina diets showed no significant increase in white blood cells (WBCs), while there was decreasing trend in the levels of neutrophils (60.46 ± 2.60%) and lymphocytes (33.53 ± 1.06%) in rats that were fed on spirulina diet (R-S) than the other tested experimental diet group. Histopathological examination revealed normal architecture of the liver with no abnormality in kidneys and spleen exhibiting safety of spirulina in both forms to mitigate protein energy malnutrition widely prevalent in developing countries..
关键词：spirulina; spirulina protein isolates; hematology; histopathology; algal toxicology.
其他关键词：spirulina;spirulina protein isolates;hematology;histopathology;algal toxicology