文章基本信息

标题：Reply to Jensen and Wang: Chimpanzees under pressure—Selection of a left ventricular structural and functional phenotype
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作者：Robert E. Shave ; Daniel E. Lieberman ; Aimee L. Drane 等
期刊名称：Proceedings of the National Academy of Sciences
印刷版ISSN：0027-8424
电子版ISSN：1091-6490
出版年度：2020
卷号：117
期号：11
页码：5574-5575
DOI：10.1073/pnas.1922202117
出版社：The National Academy of Sciences of the United States of America
摘要：We are grateful for the interest and comments provided by Jensen and Wang (1) related to our recent paper (2). As previously noted, obtaining true resting blood pressure (BP) measurements in chimpanzees is challenging, if not impossible (1). In our study, and as described in detail in the SI Appendix of ref. 2, BP was measured at least three times in each animal, and the average of these measures was used for analysis (2). We specifically excluded measurements taken within the 20-min period immediately following anesthetic delivery, in order to minimize the effects of the stress associated with anesthetic induction and the initial hypertensive response.