文章基本信息

标题：Bovine Paraoxonase-1 Activity in Oxidative Stress -
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作者：Nabil M. Taha ; Abd El Wahab A. Mandour ; Mohamed A. Lebda 等
期刊名称：Alexandria Journal of Veterinary Sciences
印刷版ISSN：1110-2047
电子版ISSN：1110-2047
出版年度：2016
卷号：51
期号：2
页码：233-238
DOI：10.5455/ajvs.229270
出版社：International Medical Journal Management and Indexing System
摘要：Association of serum paraoxonase (PON) activity and oxidative stress in dairy cows as well as the relation between PON activity and HDL-c concentration were studied. A significantly lower PON and arylesterase (ARE) activities (P˂ 0.05) was found in cows with oxidative stress (parasitic and mastitic animals) compared to clinically healthy cows. Serum glutathione peroxidase (GPX) activity and malondialdehyde (MDA) level were also markedly reduced in cows with oxidative stress where as the serum HDL-c, LDL-c and cholesterol concentration showed significant reduction than the values in healthy cows. The results indicate a higher serum TAG and vLDL-c values in normal cows than in oxidative stress cases. The total protein content, albumin and globulin concentrations were showed slightly lower values in oxidative stress than in normal cows. A decrease serum PON activity may lead to reduction of anti oxidative protection during marked oxidative stress.
关键词：Bovine paraoxonase; Oxidative stress; Glutathione peroxidase; Malondialdehide