文章基本信息

标题：Extracorporeal membrane oxygenation for acute respiratory distress syndrome in burn patients: a case series and literature update
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作者：Mehran Dadras ; Johannes M. Wagner ; Christoph Wallner 等
期刊名称：Burns & Trauma
印刷版ISSN：2321-3876
出版年度：2019
卷号：7
期号：1
页码：1-8
DOI：10.1186/s41038-019-0166-z
出版社：BioMed Central
摘要：Acute respiratory distress syndrome (ARDS) has a reported incidence of 34–43% in ventilated burn patients and is associated with a mortality of 59% in the severe form. The use and experience with extracorporeal membrane oxygenation (ECMO) in burn patients developing ARDS are still limited. We present our results and discuss the significance of ECMO in treating burn patients. A retrospective analysis of burn patients treated with ECMO for ARDS between January 2017 and January 2019 was performed. Demographic, clinical, and outcome data were collected and analyzed. Eight burn patients were treated at our institution with ECMO in the designated time period. Of these, all but one patient had inhalation injury, burn percentage of TBSA was 37 ± 23%, ABSI score was 8.4 ± 2, and R-Baux-score was 98 ± 21. Seven patients developed severe ARDS and one patient moderate ARDS according to the Berlin classification with a PaO2/FiO2 ratio upon initiation of ECMO therapy of 62 ± 22 mmHg. ECMO duration was 388 ± 283 h. Three patients died from severe sepsis while five patients survived to hospital discharge. ECMO is a viable therapy option in burn patients developing severe ARDS and can contribute to survival rates similar to ECMO therapy in non-burn-associated severe ARDS. Consequently, patients with severe respiratory insufficiency with unsuccessful conventional treatment and suspected worsening should be transferred to burn units with the possibility of ECMO treatment to improve outcome..
关键词：Extracorporeal membrane oxygenation;Acute respiratory distress syndrome;Burns;Inhalation injury;ECMO;ARDS