出版社:Sociedad Española de Dietética y Ciencias de la Alimentación (SEDCA)
摘要:Introduction: HIV-positive patient lipodystrophy is the redistribution
of body fat and may be accompanied by cardiovascular
and metabolic disorders.
Objective: Was to investigate the prevalence of lipodystrophy
in adults infected with HIV, as well as its relationship
with cardiovascular risk factors and metabolic syndrome.
Methodology: Cross-sectional study with HIV-positive
adult patients taking antiretroviral medication. Data were collected
through a questionnaire and through medical records
(viral RNA, CD4, blood glucose, LDL, HDL, triglycerides). In
addition to anthropometry (waist circumference, body weight,
height and BMI).
Results: 120 people studied among them (50.8%) had
lipodystrophy, the highest prevalence of lipodystrophy (52.1%)
occurred in males and the most widely used medication was
the NRTI + PI (24,2%). The lipodystrophy was more frequent
in patients with cardiovascular disease (68.4%), metabolic syndrome
(59.3%) and those with increased waist circumference
(55.1%). Significant differences (p <0.05) among the analyzed
subgroups (with or without lipodystrophy) occurred with
triglycerides, LDL and glucose levels. Discussion: The use of
HAART tends to improve the condition of immunity and is associated
with the onset of lipodystrophy. This also associated
with excess weight and fat accumulation predisposes to the development
of metabolic syndrome.
Conclusion: the study contributed to direct the focus and
attention profile of specialized services for HIV/AIDS.