文章基本信息

标题：Characteristics of Deceased Solid Organ Donors and Screening Results for Hepatitis B, C, and Human Immunodeficiency Viruses — United States, 2010–2017
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作者：Winston E. Abara, ; Melissa G. Collier, ; Anne Moorman, MPH 等
期刊名称：Morbidity and Mortality Weekly Report
出版年度：2019
卷号：68
期号：3
页码：61-66
DOI：10.15585/mmwr.mm6803a2
出版社：Centers for Disease Control and Prevention
摘要：What is already known about this topic? Drug overdose deaths and hepatitis C virus (HCV) infections have increased with the U.S. opioid crisis. The Public Health Service guideline for reducing unintended organ transplantation–associated hepatitis B virus (HBV), HCV, and human immunodeficiency virus (HIV) transmission describes criteria to identify increased risk donors (IRDs). What is added by this report? The number and proportion of IRDs have increased since 2010, likely because of the epidemic of opioid overdose deaths. Compared with standard risk donors, IRDs were significantly more likely to have HBV and HCV infection. Rates of nucleic acid testing have reached nearly 100%. What are the implications for public health practice? Identification of HBV, HCV, and HIV risk factors among organ donors is critical to mitigate transmission risk and ensure monitoring and appropriate treatment of recipients for posttransplant infection. Nucleic acid testing has substantially reduced the period of undetectable infection.
关键词：Hepatitis B Virus And Organ Donor Screening; Hepatitis C Virus And Organ Donor Screening; Human Immunodeficiency Virus And Organ Donors Screening; MMWR; Morbidity & Mortality Weekly Report