文章基本信息

标题：Update on Vaccine-Derived Poliovirus Outbreaks — Democratic Republic of the Congo and Horn of Africa, 2017–2018
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作者：Chukwuma Mbaeyi, DDS ; Mary M. Alleman ; Derek Ehrhardt, MSN, MPH 等
期刊名称：Morbidity and Mortality Weekly Report
出版年度：2019
卷号：68
期号：9
页码：225-230
DOI：10.15585/mmwr.mm6809a2
出版社：Centers for Disease Control and Prevention
摘要：What is already known about this topic? Prolonged person-to-person transmission of polio vaccine viruses in underimmunized populations can lead to emergence of outbreaks of paralysis from circulating vaccine-derived poliovirus (cVDPV). What is added by this report? During 2017–2018, four cVDPV type 2 outbreaks, with 42 cases to date, occurred in six provinces of the Democratic Republic of the Congo and required multiple response supplementary immunization activities (SIAs). In Somalia, concurrent cVDPV type 2 and cVDPV type 3 outbreaks occurred, first identified by sewage testing months before occurrence of 12 paralytic cases to date. What are the implications for public health practice? To promptly interrupt cVDPV transmission, country programs must effectively plan and implement timely response SIAs to optimize their quality and reach.
关键词：Vaccine;Derived Poliovirus Outbreaks; Vaccine;Derived Poliovirus Outbreaks And Democratic Republic of the Congo; Vaccine;Derived Poliovirus Outbreaks And Horn of Africa; Circulating Vaccine;Derived Poliovirus Outbreaks; Polio (poliomyelitis); Emergency Preparedness (Vaccine Safety); Outbreaks; Global Vaccination; Polio Vaccination; MMWR; Morbidity & Mortality Weekly Report