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标题：Short Communication: Association of GH, IGF1R, and PIT1 genes polymorphism with average daily gain and body measurement in Pesisir cattle
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作者：ARNIM . ; TINDA AFRIANI ; YURNALIS . 等
期刊名称：Bioteknologi
印刷版ISSN：0216-6887
出版年度：2018
卷号：10
期号：4
页码：1-5
DOI：10.13057/nusbiosci/n100404
出版社：UNS Solo
摘要：Arnim, Yurnalis, Afriani T, Putra DE. 2017. Short Communication: Association of GH, IGF1R, and PIT1 genes polymorphism with average daily gain and body measurement in Pesisir cattle. Nusantara Bioscience 10: 221-225. Growth hormone (GH) and insuLin-like growth factor I receptor (IGF1R), and Pit1 gene has important effect on growth, carcass, and meat quality traits in many species. The objectives of the present study were to study the associations of the GH/AluI, GH/MboII, IGF1R/MspI and PIT1/HinfI with growth and body measurent such as body length (BL), chest girth (CG), height withers (HW) in Pesisir cattle. A total 175 Pesisir cattle were used in this study. Weight gain, and body measurement were fitted using the General Linear Model (GLM) procedure of the SAS program. The resuLts showed significant associations between the CC genotype of the GH/MboII polymorphism and higher weight gain and height withers (p < 0.05). The GH/AluI polymorphism did not have any effect on the weight gain and body measurement. Allele frequencies were found as A: 0.374 and B: 0.626 in GH/MboII polymorphism in GH gene. The effect of GH/AluI polymorphisms was not observed on average daily gain and body measurement in Pesisir cattle (P>0.05). The effect of IGF1R/MSpI polymorphism was not observed on average daily gain but show significant association between AA and AB genotype and height withers (p < 0.005). The PIT1/HinfI polymorphism was not associated with average daily gain and body measurement in Pesisir cattle. The resuLts demostrated that the GH/MboII and GHR1/MspI polymorphisms couLd be used as a candidate gene for selection in Pesisir cattle.
关键词：Average daily gain body length; chest girth; GH; height withers; IGF1R; Pesisir cattle; PIT1; RFLP