文章基本信息

标题：Cystic Fibrosis Patients Evaluation in the Last Decades in a Referral Center, Tehran-Iran
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作者：Maryam Hassanzad ; Masoumeh Ansari ; Ali Valinejadi 等
期刊名称：International Journal of Pediatrics
印刷版ISSN：2345-5047
电子版ISSN：2345-5055
出版年度：2019
卷号：7
期号：8
页码：9997-10007
DOI：10.22038/ijp.2019.40329.3416
出版社：Mashhad University of Medical Sciences
摘要： Background
Cystic fibrosis (CF) is the most prevalent lethal chronic genetic and multivariate disease, widespread in Iranian population . The aim of this study was to evaluate the condition of patients with CF from various dimensions in the last decades in Iran. Materials and Methods
In this cross - sectional study the data were collected from disease registrydatabase of CF patients in Pediatric Respiratory Disease Research Center in Masih Daneshvari, Tehran, Iran. The patients were divided into female and male.The data were collected based on province, birthplace province, marital status, and degree of education, parental consanguinity ratio, age, and age of onset of symptoms, age of onset of diagnosis and body mass index (BMI). Results
Majority of patients (n=169, 59.3%) were male, born in Tehran province (n=81, 28.4%), and live in Tehran province (n=102, 35.8%). Majority of parents (61.1%, n=174) had consanguineous relation and the rest (n=94, 33%) did not have any consanguineous relation. Results show that mean of age, age of diagnosis, mean for expression of first symptoms and mean of time interval between the onset of symptoms and the diagnosis of the disease were 14.52, 2.51, 6.57, and 4.07 years, respectively. Results showed that high percentage of patients (n=191, 67%) had lower BMI (<18.50), and low percentage (n=3, 1.1%) showed higher BMI (>25). Correlation coefficient also showed positive relation between start age of symptoms and diagnosis age of disease. Conclusion
In Iran, CF is a multisystem disease and age for its expression is different. Since mean for time interval between the onset of symptoms and the diagnosis of the disease.
关键词：Children; Cystic fibrosis; Growth pattern; Iran; Symptoms