文章基本信息

标题：Plant factory: new resource for the productivity and diversity of human and veterinary vaccines
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作者：Shim, Byoung-Shik ; Hong, Kee-Jong ; Maharjan, Puna Maya 等
期刊名称：Clinical and Experimental Vaccine Research
印刷版ISSN：2287-3651
出版年度：2019
卷号：8
期号：2
页码：136-139
DOI：10.7774/cevr.2019.8.2.136
出版社：KoreaMed Synapse
摘要：Vaccination is one of the most successful strategies to prevent diseases caused by pathogens. Although various expression systems including Escherichia coli , yeast, insect, and mammalian cells are currently used for producing many of vaccines, these conventional platforms have the limitation of post-translational modification, high cost, and expensive scalability. In this respect, the plant-based expression system has been considered as an attractive platform to produce recombinant vaccines due to fast, cost-effective and scalable production as well as safety. This review discusses the development of plant-derived vaccines and the current stage of plant-based expression system.
关键词：Transgenic plants; Vaccines; Pharmaceuticals; Antibodies