文章基本信息

标题：Revealing the Cytotoxic Potential of Medicinal Folklore: Bombax Ceiba L.
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作者：Hafiz Tahsin Ullah Jan ; Syeda Masooma Ali ; Amna Shabbir 等
期刊名称：Journal of Bioresource Management
印刷版ISSN：2309-3854
出版年度：2017
卷号：4
期号：3
页码：4
出版社：Wright State University
摘要：Current study was intended to investigate the cytotoxic potential of Bombax ceiba L.by executing a wide range of in vitro assays. Brine shrimp lethality assay showed that stem wood’s chloroform (CH) extract was highly toxic (LC50 42.41 ± 3.40 µg/ml) followed by acetone : ethyl acetate (AC:EA) extract with LC50 value of 72.92 ± 4.41 µg/ml. n-Hexane (NH) extract of root wood part caused 70.95 ± 1.77% inhibition of THP-1 cell line at 20 μg/ml concentration (IC50 15 ± 0.56 µg/ml). NH and CH extracts of stem wood part showed promising results in protein kinase inhibitory assay with 21 ± 1.2 and 29 ± 1 mm bald ZOI (MIC= 50 µg/disc) respectively. The present findings revealed that CH and NH extracts of stem wood as well as root wood part as an enriched source of phytochemicals possessing cytotoxic potential.
关键词：Bombax ceiba L.; Cytotoxic; Folklore.