文章基本信息

标题：Preparation and Properties of Fluorescent Labels Coumarin-6/HP-β-CD Complex by Nasal Drug Delivery
本地全文：下载
作者：Mengli Tian ; Xiangyun Liu ; Lulu Song 等
期刊名称：IOP Conference Series: Earth and Environmental Science
印刷版ISSN：1755-1307
电子版ISSN：1755-1315
出版年度：2019
卷号：252
期号：2
页码：1-7
DOI：10.1088/1755-1315/252/2/022049
出版社：IOP Publishing
摘要：In order to improve the solubility and dissolution of coumarin-6, coumarin-6/HP-β-CD complex was prepared by freeze-drying. Phase solubility, UV-vis spectroscopy and fourier transformation infrared spectrum results showed that as the concentration of HP-β-CD increased, the soluble coumarin-6 in solution increased and it can be encapsulated to the cavity of HP-β-CD. Then the dissolution result showed that the complex of HP-β-CD can effectively increase the dissolution rate of coumarin-6.