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  • 标题:Unveiling Bacterial Interactions through Multidimensional Scaling and Dynamics Modeling
  • 本地全文:下载
  • 作者:Pedro Dorado-Morales ; Cristina Vilanova ; Carlos P. Garay
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:5
  • 期号:1
  • DOI:10.1038/srep18396
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:We propose a new strategy to identify and visualize bacterial consortia by conducting replicated culturing of environmental samples coupled with high-throughput sequencing and multidimensional scaling analysis, followed by identification of bacteria-bacteria correlations and interactions. We conducted a proof of concept assay with pine-tree resin-based media in ten replicates, which allowed detecting and visualizing dynamical bacterial associations in the form of statistically significant and yet biologically relevant bacterial consortia.
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