文章基本信息

标题：Roles of small RNAs in the effects of nutrition on apoptosis and spermatogenesis in the adult testis
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作者：Yongjuan Guan ; Guanxiang Liang ; Penelope A. R. Hawken 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2015
卷号：5
期号：1
DOI：10.1038/srep10372
语种：English
出版社：Springer Nature
摘要：We tested whether reductions in spermatozoal quality induced by under-nutrition are associated with increased germ cell apoptosis and disrupted spermatogenesis, and whether these effects are mediated by small RNAs. Groups of 8 male sheep were fed for a 10% increase or 10% decrease in body mass over 65 days. Underfeeding increased the number of apoptotic germ cells (P TP53 , CASP3 , FASL ). The proportion of miRNAs as a total of small RNAs was greater in well-fed males than in underfed males (P