文章基本信息

标题：Prevalence and risk factors of deep vein thrombosis in patients after spine surgery: a retrospective case-cohort study
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作者：Si-Dong Yang ; Huan Liu ; Ya-Peng Sun 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2015
卷号：5
期号：1
DOI：10.1038/srep11834
语种：English
出版社：Springer Nature
摘要：Deep vein thrombosis (DVT) is common seen in patients undergoing spine surgery. However, its prevalence and associated risk factors have not been well understood yet. This retrospective case-cohort study was designed to investigate risk factors for postoperative DVT using retrospectively collected data from department of spine surgery between 07/2013 and 07/2014. Univariate analysis and binary logistic regression analysis were used to determine risk factors for DVT. A total of 861 patients were admitted into DVT-associated analyses, including 410 males and 451 females, aged from 15 to 87 years old (median 54, IQR 18). Of them, 147 cases (17%) sustained postoperative DVT. DVT incidence was 15.9% in patients undergoing lumbar interbody fusion, 13.5% in patients treated by low-molecular-weight heparin (LMWH), while only 8.1% in patients without LMWH. However, it revealed no significant difference between LMWH group and non-LMWH group ( χ ² = 1.933, p = 0.164). Logistic regression equation was logit P = −4.09 + 0.05*X₁ − 0.55*X₂ + 0.41*X₃ + 1.41*X₇, (X₁ = age; X₂ = regions; X₃ = hypertension; X₇ = D-dimer). In this study, LMWH prophylaxis after spine surgery proved ineffective. Advanced age, D-dimer and hypertension have proved to be the risk factors for postoperative DVT in patients undergoing spine surgery.