文章基本信息

标题：Measurement of real pulsatile blood flow using X-ray PIV technique with CO2 microbubbles
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作者：Hanwook Park ; Eunseop Yeom ; Seung-Jun Seo 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2015
卷号：5
期号：1
DOI：10.1038/srep08840
语种：English
出版社：Springer Nature
摘要：Synchrotron X-ray imaging technique has been used to investigate biofluid flows in a non-destructive manner. This study aims to investigate the feasibility of the X-ray PIV technique with CO₂ microbubbles as flow tracer for measurement of pulsatile blood flows under in vivo conditions. The traceability of CO₂ microbubbles in a pulsatile flow was demonstrated through in vitro experiment. A rat extracorporeal bypass loop was used by connecting a tube between the abdominal aorta and jugular vein of a rat to obtain hemodynamic information of actual pulsatile blood flows without changing the hemorheological properties. The decrease in image contrast of the surrounding tissue was also investigated for in vivo applications of the proposed technique. This technique could be used to accurately measure whole velocity field information of real pulsatile blood flows and has strong potential for hemodynamic diagnosis of cardiovascular diseases.