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  • 标题:Feasibility of Isotope Harvesting at a Projectile Fragmentation Facility: 67Cu
  • 本地全文:下载
  • 作者:Tara Mastren ; Aranh Pen ; Graham F. Peaslee
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:4
  • 期号:1
  • DOI:10.1038/srep06706
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:The work presented here describes a proof-of-principle experiment for the chemical extraction of 67Cu from an aqueous beam stop at the National Superconducting Cyclotron Laboratory (NSCL). A 76 MeV/A 67Cu beam was stopped in water, successfully isolated from the aqueous solution through a series of chemical separations involving a chelating disk and anion exchange chromatography, then bound to NOTA-conjugated Herceptin antibodies, and the bound activity was validated using instant thin-layer chromatography (ITLC). The chemical extraction efficiency was found to be 88 ± 3% and the radiochemical yield was ≥95%. These results show that extraction of radioisotopes from an aqueous projectile-fragment beam dump is a feasible method for obtaining radiochemically pure isotopes.
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