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标题：Effect of graded hyperbaric atmospheric pressure on the quantity and composition of faecal flora
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作者：Chiranjit Maity ; Sukanta Rana ; Bikas Ranjan Pati 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2009
卷号：21
期号：2
页码：104-108
DOI：10.1080/08910600902992725
出版社：Microbial Ecology in Health and Disease
摘要：Objectives: The ecosystem of the intestinal flora is always dynamic and it is maintained even in the changing chemical and physical environment of the host. The effects of the physical environment such as atmospheric pressure on the composition of intestinal flora has not been studied previously. Considering this, an in vitro experiment was designed to explore the effects of hyperbaromatric pressure on the faecal flora of the rat. Materials and methods: Faecal samples from male albino rat were exposed to graded hyperbaric conditions (122 and 170 kilopascal, kPa) for different time periods (1, 3 and 5 h). Total aerobes, total anaerobes, Escherichia coli, Bifidobacterium spp. and Clostridium perfringens present in the faecal samples were quantified by specific culture-based methods. Variation in their number in comparison to control conditions was analysed statistically (ANOVA and Tukey t test). Results: The numbers of total aerobes and E. coli were increased with the increase in air pressure, whereas a reduction in numbers was recorded for total anaerobes, Bifidobacterium spp. and C. perfringens. Variations of these groups of bacteria in relation to dose and duration of hyperbaric treatment were also recorded. Conclusion: Air pressure is an important exogenous factor that strongly regulates the composition of the faecal flora.
关键词：barometric pressure ; faecal flora ; Clostridium perfringens ; Bifidobacterium spp