文章基本信息

标题：Fermented milk containing Lactobacillus GG alleviated DSS-induced colitis in mice and activated epidermal growth factor receptor and Akt signaling in intestinal epithelial cells
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作者：Kazutoyo Yoda ; Fang He ; Kenji Miyazawa 等
期刊名称：Microbial Ecology in Health and Disease
印刷版ISSN：1651-2235
出版年度：2012
卷号：23
期号：1
DOI：10.3402/mehd.v23i0.18586
出版社：Microbial Ecology in Health and Disease
摘要：Lactobacillus rhamnosus GG was assessed for its ability to alleviate DSS-induced colitis in mice and activate epidermal growth factor receptor and Akt signaling in intestinal epithelial cells. In this study mice were treated with DSS to induce colitis and they were given Lactobacillus GG fermented milk to assess the effect of probiotic on colitis. Lactobacillus GG fermented milk significantly reduced the colitis associated changes suggesting a protective effect against DSS induced colitis.
关键词：Lactobacillus GG ; fermented milk ; colitis ; EGF receptor ; intestinal epithelial cell