文章基本信息

标题：Functional Status of Maternal Thyroid Gland in Eclampsia
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作者：M Hafizur Rahman ; Mahbub Ara Chowdhury ; Shahin Mahmuda 等
期刊名称：TAJ: Journal of Teachers Association
印刷版ISSN：1019-8555
出版年度：2018
卷号：31
期号：1
页码：9-14
DOI：10.3329/taj.v31i1.41567
语种：English
出版社：Teachers Association of Rajshahi Medical College
摘要：Marked changes in maternal thyroid activity occur in pregnancy. During pregnancy bodily hormonal changes and metabolic demands result in complex alteration in the bio-chemical parameters of thyroid activities. Besides these, thyroid enlargement, increased thyroid capability for iodine uptake and increase in basal metabolic rate are evidential though these findings are not usually associated with symptoms of hyperthyroidism in pregnancy. Serum concentration of thyroid hormone thyroxine and triiodothyronine in complicated pregnancy like eclamptic toxemia is another field of controversy. To evaluate the changes in thyroid function in normal pregnancy and eclamptic toxemia, a study was undertaken in Rajshahi Medical College Hospital. We collected serum specimens from non pregnant but married women, normal 3^rdtrimester pregnant women and patients with eclampsia at 3^rdtrimester of pregnancy and measured serum concentrations of total and free thyroxine (TT₄& FT₄) and total and free triiodothyronine (TT₃& FT₃) by using RIA. Among the study subjects, 10 women were married but non pregnant, 12 women were in their 3^rdtrimester of normal pregnancy and 32 patients of eclamptic toxemia with 3^rdtrimester of pregnancy. In normal pregnancy, FT₄and FT₃levels remained normal while TT₄and TT₃levels were elevated. In patients with toxemia of pregnancy, the mean serum TT₃concentration was significantly lower than that of normal pregnancy and the serum FT₃concentrations were below the normal pregnancy range. The mean serum TT₄and FT₄concentrations in patients with eclampsia were however, significantly higher than those in normal pregnant women. TAJ 2018; 31(1): 9-14
关键词：Functional Status;Thyroid Gland;Eclampsia