文章基本信息

标题：Morphological Patterns of Elastic and Reticulum Fibers in Breast Lesions
本地全文：下载
作者：Abdelbaset Mohamed Elasbali ; Ziad Al-Onzi ; Alneil Hamza 等
期刊名称：Health
印刷版ISSN：1949-4998
电子版ISSN：1949-5005
出版年度：2018
卷号：10
期号：12
页码：1625-1633
DOI：10.4236/health.2018.1012122
语种：English
出版社：Scientific Research Publishing
摘要：Background: The difficulty with histopathology diagnosis is the presence of numerous benign reactive breast lesions with morphological features mimic malignant lesions. Thus, the objective of this study was to assess the merit of morphological patterns of elastic and reticular fibers in differential diagnosis of benign and malignant breast lesions. Methodology: Fifty biopsies were obtained from females with breast Lesions (25 breast carcinoma and 25 benign lesions), their ages ranging from 17 to 85 years with mean age of 39 years old. Morphologic demonstrations of elastic and reticular fibers were performed using conventional histochemical procedures. Results: Intense grades of elastic fiber staining were achieved with carcinoma tissues. Dwindled grades of elastic fiber staining were detected with fibrocystic changes. Elastic fibers in breast carcinoma are significantly increased compared to benign breast lesions P < 0.05. Reticular fibers have indicated relatively similar presentation in benign and malignant breast lesions. Conclusion: Histochemical quantifications of elastic and reticular fibers can assist in routine diagnosis of breast lesions. Elastic fibers significantly increase in breast carcinoma compared to benign breast lesions.
关键词：Breast Cancer;Benign Breast Lesions;Reticular Fibers;Elastic Fibers