文章基本信息

标题：Radiogenomic Analysis of F-18-Fluorodeoxyglucose Positron Emission Tomography and Gene Expression Data Elucidates the Epidemiological Complexity of Colorectal Cancer Landscape
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作者：Efstathios–Iason Vlachavas ; Eleftherios Pilalis ; Olga Papadodima 等
期刊名称：Computational and Structural Biotechnology Journal
印刷版ISSN：2001-0370
出版年度：2019
卷号：17
页码：177-185
DOI：10.1016/j.csbj.2019.01.007
出版社：Computational and Structural Biotechnology Journal
摘要：Purpose Transcriptomic profiling has enabled the neater genomic characterization of several cancers, among them colorectal cancer (CRC), through the derivation of genes with enhanced causal role and informative gene sets. However, the identification of small-sized gene signatures, which can serve as potential biomarkers in CRC, remains challenging, mainly due to the great genetic heterogeneity of the disease.
关键词：18 F-FDG PET ; Radiogenomics ; Colorectal cancer ; Microarray analysis ; Translational bioinformatics ; TCGA