文章基本信息

标题：THE USE OF HAMMETT CONSTANTS TO UNDERSTAND THE NON-COVALENT BINDING OF AROMATICS
本地全文：下载
作者：Michael Lewis ; Christina Bagwill ; Laura K.E. Hardebeck 等
期刊名称：Computational and Structural Biotechnology Journal
印刷版ISSN：2001-0370
出版年度：2012
卷号：1
期号：1
DOI：10.5936/csbj.201204004
语种：
出版社：Computational and Structural Biotechnology Journal
摘要：Non-covalent interactions of aromatics are important in a wide range of chemical and biological applications. The past two decades have seen numerous reports of arene-arene binding being understood in terms Hammett substituent constants, and similar analyses have recently been extended to cation-arene and anion-arene binding. It is not immediately clear why electrostatic Hammett parameters should work so well in predicting the binding for all three interactions, given that different intermolecular forces dominate each interaction. This review explores such anomalies, and summarizes how Hammett substituent constants have been employed to understand the non-covalent binding in arene-arene, cation-arene and anion-arene interactions.
关键词：Hammett Constants ; Arene-Arene Interactions ; Cation-Arene Interactions ; Aromatics