文章基本信息

标题：Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer
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作者：Wei Li ; Han Liu ; Weikun Qian 等
期刊名称：Computational and Structural Biotechnology Journal
印刷版ISSN：2001-0370
出版年度：2018
卷号：16
页码：479-487
DOI：10.1016/j.csbj.2018.10.006
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出版社：Computational and Structural Biotechnology Journal
摘要：Background Diabetes mellitus and pancreatic cancer are intimately related. Our previous studies showed that high levels of blood glucose promote epithelial-mesenchymal transition of pancreatic cancer. In this study, we evaluated the relationship between hyperglycemia and hypoxic tumor microenvironments.
关键词：Hyperglycemia ; Hypoxia ; HIF-1α ; Metastasis ; Pancreatic cancer