文章基本信息

标题：Recent Advances on the Molecular Mechanism of Cervical Carcinogenesis Based on Systems Biology Technologies
本地全文：下载
作者：Min Lin ; Miaomiao Ye ; Junhan Zhou 等
期刊名称：Computational and Structural Biotechnology Journal
印刷版ISSN：2001-0370
出版年度：2019
卷号：17
页码：241-250
DOI：10.1016/j.csbj.2019.02.001
出版社：Computational and Structural Biotechnology Journal
摘要：Cervical cancer is one of the common malignancies in women worldwide. Exploration of pathogenesis and molecular mechanism of cervical cancer is pivotal for development of effective treatment for this disease. Recently, systems biology approaches based on high-throughput technologies have been carried out to investigate the expression of some genes and proteins in genomics, transcriptomics, proteomics, and metabonomics of cervical cancer. Compared with traditional methods，systems biology technology has been shown to provide large of information regarding prognostic biomarkers and therapeutic targets for cervical cancer. These molecular signatures from system biology technology could be useful to understand the molecular mechanisms of cervical cancer development and progression, and help physicians to design targeted therapeutic strategies for patients with cervical cancer.
关键词：Cervical cancer ; Systems biology ; Genomics ; Transcriptomics ; Proteomics