文章基本信息

标题：Variant anatomy of the buccal nerve
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作者：Mayank Patel ; Joe Iwanaga ; Shogo Kikuta 等
期刊名称：Anatomy & Cell Biology
印刷版ISSN：2093-3665
出版年度：2019
卷号：52
期号：1
页码：82-83
DOI：10.5115/acb.2019.52.1.82
出版社：Anatomy and Cell Biology
摘要：Lipid bilayer membranes are soft, fluid, and dynamic architecture where molecules are constantly moving and thermally fluctuating under physiological conditions. In this review, a strategy to quantify molecular dynamics in membranes is introduced by utilizing solution-state NMR spectroscopy as a versatile, noninvasive technique. The dynamics involves lateral diffusion and protrusion motion, in parallel and vertical direction to the membrane surface. Dynamical behavior of small-sized drugs, chemicals, and peptides is also reviewed in relation to the lipid movements in membranes, on the basis of recent multinuclear NMR in combination with the pulsed field gradient technique. Finally, in-cell NMR method is introduced as a promising technique to capture drug transport processes in real time, to shed light on mechanisms of deliveries to living cells without perturbation of the system.
关键词：anatomical variation; Anatomy; Buccal nerve; Trigeminal nerve; Buccal nerve block