The study objectives are to investigate the influence of human resources information system benefits and barriers on staff performance in Al-Balqa applied university. To fulfill such objectives, a self-administrated questionnaire was used for the purpose of collecting the required date. The questionnaire was distributed over the research sample that was consisted of 200 subjects selected randomly. Descriptive methodology was use. Collected data were analyzed through using the SPSS. The research concluded that human resource information system implementation impacts positively university performance. The results also revealed that an implementation human resource information system barrier affects negatively university staff performance.