文章基本信息

标题：Critical Shear Stress is Associated with Diabetic Kidney Disease in Patients with Type 2 Diabetes
本地全文：下载
作者：Seung Min Chung ; Jung Hyun Oh ; Jun Sung Moon 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：908
DOI：10.1038/s41598-018-19274-5
语种：English
出版社：Springer Nature
摘要：or a urine albumin-to-creatinine ratio (uACR) ≥30 mg/g. CSS was significantly higher in patients with DKD than in those without (317.43 ± 125.11 vs 385.22 ± 182.89, p < 0.001). Compared to the lowest CSS tertile, the highest CSS tertile was independently associated with the risk of DKD after adjusting for age, sex, duration of diabetes, presence of hypertension and haemoglobin. The cut-off value of CSS for DKD was approximately 310 mPa. These results suggest that haemorheologic changes may contribute to DKD, and further prospective studies are warranted to determine the role of CSS as a DKD screening tool.