文章基本信息

标题：PCSK9 induces a pro-inflammatory response in macrophages
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作者：Chiara Ricci ; Massimiliano Ruscica ; Marina Camera 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：2267
DOI：10.1038/s41598-018-20425-x
语种：English
出版社：Springer Nature
摘要：, respectively). Finally, a positive correlation between PCSK9 and TNF-α plasma levels of healthy adult subjects (males 533, females 537) was observed (B = 8.73, 95%CI 7.54 ÷ 9.93, p < 0.001). Taken together, the present study provides evidence of a pro-inflammatory action of PCSK9 on macrophages, mainly dependent by the LDLR.