文章基本信息

标题：The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity
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作者：Naoya Sawamura ; Mariko Yamada ; Miku Fujiwara 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：2459
DOI：10.1038/s41598-018-20911-2
语种：English
出版社：Springer Nature
摘要：, the binding of AMPK and CRBN was partly restored. These results suggest that thalidomide inhibits the activity of AMPK via CRBN under oxidative stress and suppresses nerve cell death.