文章基本信息

标题：Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe
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作者：Hadis Honarvar ; Enrica Calce ; Nunzianna Doti 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：2998
DOI：10.1038/s41598-018-21283-3
语种：English
出版社：Springer Nature
摘要：In-labeled A9 demonstrated nanomolar affinity to HER2-expressing BT474 cells and favorable biodistribution profile in NMRI mice. This study suggests that the peptide A9 represents a good lead candidate for development of molecular probe, to be used for imaging purposes and for the delivery of cytotoxic agents.