文章基本信息

标题：Tailoring light delivery for optogenetics by modal demultiplexing in tapered optical fibers
本地全文：下载
作者：Marco Pisanello ; Filippo Pisano ; Leonardo Sileo 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：4467
DOI：10.1038/s41598-018-22790-z
语种：English
出版社：Springer Nature
摘要：> 10° this relationship is linear. This mode-division demultiplexing property of the taper was confirmed with a ray tracing model and characterized for 473 nm and 561 nm light in quasi-transparent solution and in brain slices, with the two wavelengths used to illuminate simultaneously two different regions of the brain using only one waveguide. The results presented in this manuscript can guide neuroscientists to design their optogenetic experiments on the base of this mode-division demultiplexing approach, providing a tool that potentially allow for dynamic targeting of regions with diverse extension, from the mouse VTA up to the macaque visual cortex.