文章基本信息

标题：Biotic and environmental stress induces nitration and changes in structure and function of the sea urchin major yolk protein toposome
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作者：Immacolata Castellano ; Oriana Migliaccio ; Giarita Ferraro 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：4610
DOI：10.1038/s41598-018-22861-1
语种：English
出版社：Springer Nature
摘要：-binding affinity of the protein. After 3 months' detoxification, ovatoxin was undetectable, and the number of nitric oxide-modified tyrosines was reduced. However, the nitration of specific residues was irreversible and occurred also in embryos treated with metals, used as a proxy of environmental pollutants. The structural and functional changes of toposome caused by nitration under adverse environmental conditions may be related to the defective development of sea urchins' progeny.