文章基本信息

标题：Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs
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作者：Kai Ding ; Ziyuan Zhou ; Shurong Hou 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：5205
DOI：10.1038/s41598-018-23482-4
语种：English
出版社：Springer Nature
摘要：(an inflammatory marker) levels compared to the currently available drug celecoxib. This is the first demonstration in wild-type mice that mPGES-1 is truly a promising target for the next generation of anti-inflammatory drugs.