文章基本信息

标题：The oscillation of intracellular Ca2+ influx associated with the circadian expression of Piezo1 and TRPV4 in the bladder urothelium
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作者：Tatsuya Ihara ; Takahiko Mitsui ; Yuki Nakamura 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：5699
DOI：10.1038/s41598-018-23115-w
语种：English
出版社：Springer Nature
摘要：in WT mice. We conclude that SBF may have a circadian rhythm, which is created by functional circadian changes of Piezo1 and TRPV4 being controlled by clock genes to be active during wakefulness and inactive during sleep. Abnormalities of clock genes disrupt SBF, and induce nocturia.