文章基本信息

标题：Molecular design of radiocopper-labelled Affibody molecules
本地全文：下载
作者：Vladimir Tolmachev ; Tove J. Grönroos ; Cheng-Bin Yim 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：6542
DOI：10.1038/s41598-018-24785-2
语种：English
出版社：Springer Nature
摘要：Cu-CB-TE2A-GEEE-ZHER2:342 was 16 ± 6%ID/g and tumor-to-blood ratio was 181 ± 52. In conclusion, a combination of the cross-bridged CB-TE2A chelator and Gly-Glu-Glu-Glu spacer is preferable for radiocopper labelling of Affibody molecules and, possibly, other scaffold proteins having high renal re-absorption.