文章基本信息

标题：Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer
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作者：E. M. Kennedy ; D. R. Powell ; Z. Li 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：6709
DOI：10.1038/s41598-018-24755-8
语种：English
出版社：Springer Nature
摘要：Si ions, discriminated tumor from normal tissue for human lung adenocarcinomas and squamous cell carcinomas. Thus, high-LET radiation exposure leaves a lasting imprint on the epigenome, and affects sites relevant to human lung cancer. These methylation signatures may prove useful in monitoring the cumulative biological impact and associated cancer risks encountered by astronauts in deep space.