文章基本信息

标题：Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering
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作者：Ingy I. Abdallah ; Ronald van Merkerk ; Esmée Klumpenaar 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：9961
DOI：10.1038/s41598-018-28177-4
语种：English
出版社：Springer Nature
摘要：by 5 times. This variant can be used to enhance amorphadiene production and in turn artemisinin biosynthesis. Our findings provide the basis for the first step in improving industrial production of artemisinin and they open up possibilities for further engineering and understanding of ADS.