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  • 标题:Structural and functional characterization of suramin-bound MjTX-I from Bothrops moojeni suggests a particular myotoxic mechanism
  • 本地全文:下载
  • 作者:Guilherme H. M. Salvador ; Thiago R. Dreyer ; Antoniel A. S. Gomes
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:10317
  • DOI:10.1038/s41598-018-28584-7
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:-like/suramin complexes. Thus, we suggested a novel myotoxic mechanism for MjTX-I that may be inhibited by suramin. These results can further contribute to the search for inhibitors that will efficiently counteract local myonecrosis in order to be used as an adjuvant of conventional serum therapy.
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