文章基本信息

标题：Identification of an INa-dependent and Ito-mediated proarrhythmic mechanism in cardiomyocytes derived from pluripotent stem cells of a Brugada syndrome patient
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作者：Dongrui Ma ; Zhenfeng Liu ; Li Jun Loh 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：11246
DOI：10.1038/s41598-018-29574-5
语种：English
出版社：Springer Nature
摘要：densities of BrS1 and CON1 were comparable and increased from 1.0 Hz to 0.1 Hz by ~ 100%. These data indicate that a repolarization deficit could be a mechanism underlying BrS.