文章基本信息

标题：MicroRNA in diagnosis and therapy monitoring of early-stage triple-negative breast cancer
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作者：Mustafa Kahraman ; Anne Röske ; Thomas Laufer 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：11584
DOI：10.1038/s41598-018-29917-2
语种：English
出版社：Springer Nature
摘要：). Our results also suggest that changes in miRNA expression during NCT may have predictive potential to predict pathological complete response (pCR). In conclusion we report that miRNA expression measured from blood facilitates early and minimally-invasive diagnosis of basal-like TNBC. We also demonstrate that NCT has a significant influence on miRNA expression. Finally, we show that blood-borne miRNA profiles monitored over time have potential to predict pCR.