文章基本信息

标题：Neprilysin inhibition promotes corneal wound healing
本地全文：下载
作者：Rachel M. Genova ; Kacie J. Meyer ; Michael G. Anderson 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：14385
DOI：10.1038/s41598-018-32773-9
语种：English
出版社：Springer Nature
摘要：mice compared to WT controls 3 days after injury. Daily intraperitoneal administration of the NEP inhibitor thiorphan also accelerated corneal wound healing after alkali injury in WT mice. Collectively, our data identify a previously unknown role of NEP in the cornea, in which pharmacologic inhibition of its activity may provide a novel therapeutic option for patients with corneal injury.