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  • 标题:Selective detections of single-viruses using solid-state nanopores
  • 本地全文:下载
  • 作者:Akihide Arima ; Makusu Tsutsui ; Ilva Hanun Harlisa
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:16305
  • DOI:10.1038/s41598-018-34665-4
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:pore orifice. We demonstrate identifications of allotypes with 68% accuracy at the single-virus level via pattern classifications of the ionic current signatures. We also show that this discriminability becomes >95% under a binomial distribution theorem by ensembling the pulse data of >20 virions. This simple mechanism is versatile for point-of-care tests of a wide range of flu types.
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