文章基本信息

标题：The geranyl acetophenone tHGA attenuates human bronchial smooth muscle proliferation via inhibition of AKT phosphorylation
本地全文：下载
作者：Hui Min Yap ; Yu Zhao Lee ; Hanis Hazeera Harith 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：16640
DOI：10.1038/s41598-018-34847-0
语种：English
出版社：Springer Nature
摘要：. The inhibitory effect of tHGA was demonstrated to be related to its direct inhibition of AKT phosphorylation, as well as inhibition of JNK and STAT3 signal transduction. Our findings highlight the anti-remodeling potential of this drug lead in chronic airway disease.