文章基本信息

标题：Electrophysiological properties of human beta-cell lines EndoC-βH1 and -βH2 conform with human beta-cells
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作者：Benoît Hastoy ; Mahdieh Godazgar ; Anne Clark 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：16994
DOI：10.1038/s41598-018-34743-7
语种：English
出版社：Springer Nature
摘要：channels. Exocytosis presented a similar kinetics to human primary beta cells. The ultrastructure of these cells shows insulin vesicles composed of an electron-dense core surrounded by a thin clear halo. We conclude that the EndoC-βH1 and -βH2 cells share many features of primary human β-cells and thus represent a useful experimental model.