文章基本信息

标题：L-Proline functionalized magnetic nanoparticles: A novel magnetically reusable nanocatalyst for one-pot synthesis of 2,4,6-triarylpyridines
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作者：Ali Maleki ; Razieh Firouzi-Haji
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：17303
DOI：10.1038/s41598-018-35676-x
语种：English
出版社：Springer Nature
摘要：In this work, an efficient method for the immobilization of L-proline on magnetic nanoparticles was offered and evaluated as a recoverable magnetic nanocatalyst for synthesis of 2,4,6-triarylpyridines through one-pot three-component reaction of acetophenone, aryl aldehydes and ammonium acetate. This article is the first report of the catalytic application of L-proline functionalized magnetic nanoparticles in organic reactions as a magnetic nanocatalyst. This novel magnetic nanocatalyst proved to be effective and provided the products in high to excellent yield under solvent-free conditions. The structure of obtained nanoparticles was characterized by Fourier transform infrared spectrophotometry (FT-IR), field-emission scanning electron microscopy (FE-SEM), thermogravimetric analysis (TGA) and energy-dispersive X-ray spectroscopy (EDX). TGA result revealed that it is stable up to 200 °C for using as a catalyst in organic reactions. FE-SEM image of the synthesized nanocatalyst showed that it has nearly core-shell spherical shape and uniform size distribution with an average size about 80 nm. Moreover, the catalyst could be easily recovered by facile separation by magnetic forces and recycled for several times without significant loss of its catalytic activity. The benefits of this study are simplicity, nontoxicity, low cost, simple workup, and an environmentally benign nature.