文章基本信息

标题：SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain
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作者：Alpna Tyagi ; Christy U Nguyen ; Thomas Chong 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：17547
DOI：10.1038/s41598-018-35890-7
语种：English
出版社：Springer Nature
摘要：mice when fed a calorie-rich western diet. The observations of this study suggest that SIRT3 deficiency-induced brain mitochondrial dysfunction and neuroinflammation in metabolic syndrome may play a role in late-life cognitive decline.