文章基本信息

标题：Adult hippocampal neurogenesis occurs in the absence of Presenilin 1 and Presenilin 2
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作者：Jagroop Dhaliwal ; Timal S. Kannangara ; Michael Vaculik 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：17931
DOI：10.1038/s41598-018-36363-7
语种：English
出版社：Springer Nature
摘要：inducible genetic approach, demonstrated no changes in the proliferation, survival, or differentiation of adult-generated cells. Therefore, unlike their significant role in neurogenesis during embryonic development, presenilins are not required for cell-intrinsic regulation of adult hippocampal neurogenesis.