文章基本信息

标题：The mineralocorticoid receptor is essential for stress axis regulation in zebrafish larvae
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作者：Erin Faught ; Mathilakath M. Vijayan
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：18081
DOI：10.1038/s41598-018-36681-w
语种：English
出版社：Springer Nature
摘要：mutants showed a delayed, but sustained cortisol response post-stressor. Both these receptors are involved in stress-related behaviour, as the loss of either receptors abolished the glucocorticoid-mediated larval hyperactivity to a light stimulus. Overall, the results underscore a key physiological role for MR signalling in ray-finned fishes, and we propose that the regulation of the highly conserved stress axis as the original function of this receptor.