文章基本信息

标题：In vivo assessment of increased oxidation of branched-chain amino acids in glioblastoma
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作者：Eul Hyun Suh ; Edward P. Hackett ; R. Max Wynn 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2019
卷号：9
期号：1
页码：1-9
DOI：10.1038/s41598-018-37390-0
出版社：Springer Nature
摘要：C]leucine to glioma-bearing rats verified the increased oxidation of leucine in glioma tissue. Both the in vivo hyperpolarized KIC imaging and the leucine infusion study indicate that KIC catabolism is upregulated through BCAT/BCKDC and further oxidized via the citric acid cycle in F98 glioma.